Friends are urging Sharon Osbourne to take action against the manufacturers of the drug.
'Nobody else seems to look like Sharon after taking it,' another friend told me. 'It has completely changed her. She looks awful at times, and she knows that Ozempic hasn't been so kind to her.'
There is another reason why Sharon is so worried about her health, and that's because Ozzy is extremely unwell.
The rock star, who spent years abusing alcohol and drugs, was injured in a quad bike accident in 2003, which left him needing spinal surgeries and frequently using a wheelchair. Then, in 2020, he revealed he had been diagnosed with Parkinson's disease.
The couple, whose 42-year marriage has endured despite Ozzy's infidelities and relapses, had been looking forward to returning to the UK where Sharon had been masterminding renovations to their Buckinghamshire house.
When Sharon Osbourne was a judge on The X Factor, she had a reputation for straight-talking. There wasn't a single subject, no matter how intimate, inappropriate or embarrassing, she considered off-limits. It got her into a lot of trouble at times, but also made her a lot of fun.
The 72-year-old grandmother, TV personality, wife and former manager of Black Sabbath frontman Ozzy was particularly open about her 20-year relationship with cosmetic surgery, admitting to a full facelift, tummy tuck, eyelift, breast implants, abdominoplasty and Botox over the years.
At one point, she said she had 'not that much skin left to stretch, pull or cut' and complained that her last eyelift left her 'looking like f****** Cyclops'.
Nowadays, there's one subject, however, that has stopped being funny - and that's her dramatic weight loss.
Sharon - a former bulimic who has always struggled with her body image - started using the weight-loss injection Ozempic at the start of 2023 and lost more than four stone in months. With typical chutzpah, last year she confessed all to American broadcaster Howard Stern, saying: 'It's not a sin to use Ozempic if you have a weight problem, so why not talk about it?' But a year after coming off the medication - which is licensed to treat type 2 diabetes in the US but can be prescribed there for weight management - she's been left struggling to eat and today barely weighs seven stone, which is far too thin for her 5ft 2in frame.
She's desperately worried about her health, friends say, as is everyone close to her - including her equally frail husband Ozzy, 76.
'Sharon simply can't eat,' said a friend. 'If you go for dinner with her, she pushes her food around her plate. She struggles to eat a bowl of fruit. She has stopped taking Ozempic but the after effects have been awful for her.She didn't expect it to end up like this. She looks in the mirror, she knows what she looks like. 'She's gaunt, she's so thin and while she has been very trim for a long time, this is something else and she knows it.'
'Does she wish she never touched Ozempic? Yes.' Other She saw it as the place for them to see out their days.
However, Ozzy's precarious health has left him confined to their home in Los Angeles - where he has full-time carers.
'She is worried. He's the love of her life and he is struggling,' a friend says. 'Their plans to come home and have a lovely life are not happening at the moment.'
Ozzy is also worried about his wife and friends say that if anything happened to her he would be 'inconsolable'. The couple, whose TV show The Osbournes propelled them to stardom in 2002, have been working on a ten-part series, called Home to Roost, about their plans to leave the US - where they've lived on and off for nearly 30 years.
Sharon's plans for their UK home include building a 'rehabilitation wing' to help the singer learn to walk. An extension with enough space for round-the-clock carers has been proposed.
Also factored in are 'discreet grab rails and aids', plus a pool house orangery, exercise studio and garden room with views of a lake.
It's unclear whether Ozzy will ever able to make the trip - or indeed if Sharon can support him as her health concerns grow. It's fair to say she has never trodden the conventional path.
London-born Sharon first met Ozzy in 1970 when she was only 18 and her father, Don Arden, was managing Black Sabbath.
But sparks didn't fly between them until many years later. That happened after Ozzy found himself kicked out of the band due to substance abuse issues. It was only when Sharon helped him recover that they fell in love in 1979. She also took over as his manager the same year, encouraging him to pursue a solo career.
They married in July 1982 - months after Ozzy finalised his divorce from his first wife, Thelma Riley. They went on to have three children: Aimee in 1983, Kelly in 1984 and Jack in 1985.
But three pregnancies left Sharon struggling with her weight. At one point she was more than 16 stone. She once said: 'When Ozzy and I were first together, I'd try to keep up with his drinking but I was useless. One wine gum and I'm on the floor. No, my weakness has always been food. When I'm happy, I eat. When I'm sad, I eat. I was a pig.
'At my heaviest, I weighed 225lb — that's just over 16 stone. And I'm only 5ft 2in. I wasn't happy. Sure on the surface, but at night in bed alone I was very unhappy.'
She had a gastric band operation in 1999, which enabled her to lose eight stone. But she had it removed in 2006 as she didn't like how it made her feel and switched to the high-protein Atkins diet.
There was another worrying episode in 2002 when she was diagnosed with colon cancer. A decade later, she underwent a precautionary double mastectomy after finding she carries a gene which increases the chance of breast cancer.
Her popularity in the Noughties will also have focused yet more attention on her appearance.
Having decided to give Ozempic a try two years ago, initially, she was pleased with the results but was shocked at the drug's impact.
When she appeared on Celebrity Big Brother last year, viewers were concerned by how thin she'd become. Sharon admitted in February she feared she had damaged her metabolism. Whatever happens, it's clear the Osbournes have yet more obstacles to surmount before they can enjoy the peaceful life they have planned.
